Biochem/physiol Actions

Cell permeable: no

Reversible: no

Flavonoid, antioxidant. Inhibits lipogenesis in cancer cells, most likely by targeting fatty acid synthase activity.

Product does not compete with ATP.

Primary TargetAn antioxidant flavonoid that scavenges superoxide

General description

An antioxidant flavonoid that scavenges superoxide (1.5 x 10⁵ M^-1 s^-1) and suppresses the cytotoxicity of superoxide and hydrogen peroxide in Chinese hamster V79 cells.

An antioxidant flavonoid that suppresses the cytotoxicity of superoxide ions and hydrogen peroxide in Chinese hamster V79 cells.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Kostyuk, V.A., et al. 1998. Arch. Biochem. Biophys. 355, 43.Bors, W., et al. 1995. Free Radic. Biol. Med. 19, 45.Nakayama, T., et al. 1994. Cancer Res. 54, 1991s.Nakayama, T., et al. 1993. Biochem. Pharmacol. 45, 265.

Packaging

25 mg in Glass bottle

Packaged under inert gas

Warning

Toxicity: Harmful (C)